peer-reviewed journal articles

Piercey, C. J., Hetelekides, E., & Karoly, H.C. (2024). Simultaneous cannabis and psychedelic use among festival and concert attendees in Colorado: characterizing enhancement and adverse reactions using mixed methods. PDF

Piercy, C. J., Gray, B., Sung, A., Henry, D., & Karoly, H.C. (2024). Protective behavioral strategies for psychedelic use: A mini review of the evidence.

Piercey, C. J., Mataczynski, M., Stallsmith, V., Emery, N.N., & Karoly, H.C. (2024). Examining associations between cannabis use disorder and measures of weekly and within-day cannabis frequency, quantity, and potency in college students.

Karoly, H. C., Prince, M. A., & Conner, B. T. (2024). Alcohol first, cannabis last: Identification of an especially risky use pattern among individuals who co-use alcohol and cannabis. PDF

Sznitman, S. R., Martin‐Willett, R., Ma, W., Karoly, H. C., & Bidwell, L. C. (2024). Daily diary study of associations between alcohol, cannabis, co‐use and sleep quality in individuals with intentions to use cannabis to cope with anxiety. PDF

Stallsmith, V. T., Karoly, H. C., Prince, M. A., Graham, D., Bell, C., & Tompkins, S. A. (2024). Exploring daily-level characteristics of the cannabis-exercise relationship. PDF

Stallsmith, V. T., Piercey, C. J., Mataczynski, M. M., Karoly, H. C., & Emery, N. N. (2024). Probing the paradox: Investigating the impact of affect, exercise type, and cannabis use on the alcohol-exercise relationship in college students PDF

Hetelekides, E. Emery, N. N., Prince, M. A., Conner, B. T., & Karoly, H. C. (2023). Alcohol use prior to cannabis use elevates peak heart rate: Preliminary data from a laboratory study of co-administered alcohol and legal-market cannabis.

Douglass, M. A., Stanley, L. R., Karoly, H. C., Prince, M. A., Crabtree, M. A., & Swaim, R. C. (2023). Patterns of simultaneous and nonsimultaneous use of cannabis and alcohol among American Indian adolescents.

Gowin, J. L, Kirk-Provencher, K. T., Karoly, H. C., & Schacht, J. P. (2023). Structural and functional imaging of alcohol’s effects on the brain.

Ross, J. M, Karoly, H. C., Zellers, S. M., Ellingson, J. M., Corley, R. P., Iacono, W. G., Hewitt, J. K., McGue, M., Vrieze, S., & Hopfer, C. J. (2023). Addendum to “Evaluating substance use outcomes of recreational cannabis legalization using a unique co-twin control design.”

Ross, J. M, Karoly, H. C., Zellers, S. M., Ellingson, J. M., Corley, R. P., Iacono, W. G., Hewitt, J. K., McGue, M., Vrieze, S., & Hopfer, C. J. (2023). Evaluating substance use outcomes of recreational cannabis legalization using a unique co-twin control design.

Skrzynski, C. J., Karoly, H. C., Ellingson, J. M., Hagerty, S. L., Bryan, A. D., & Hutchison, K. E. (2023). Comparing the efficacy of mindfulness-based relapse prevention versus relapse prevention for alcohol use disorder: A randomized control trial. PDF

Martin-Willett, R., Skrzynski, C. J., Karoly, H. C., Elmore, J. S., & Bidwell, L. C. (2023). Baseline affective symptomatology moderates acute subjective effects of high potency THC and CBD cannabis concentrates. PDF

Karoly, H. C., Drennan, M. L., Prince, M. A., Zulic, L., & Dooley, G. (2023). Consuming oral cannabidiol prior to a standard alcohol dose has minimal effect on breath alcohol level and subjective effects of alcohol. PDF

Karoly, H. C., Conner, B. T., & Prince, M. A. (2023) Associations between alcohol and cannabis use order, frequency, quantity, and consequences in a college sample of individuals who co‐use alcohol and cannabis. PDF

Karoly, H. C., Prince, M. A., Emery, N. N., Smith, E. E., Piercey, C. J., & Conner, B. T. (2022). Protocol for a mobile laboratory study of co-administration of cannabis concentrates with a standard alcohol dose in humans. PDF

Bidwell L.C., Karoly, H.C., Ortiz Torres, M., Master, A., Bryan. A.D., Hutchison, K.E. (2022). A Naturalistic Study of Orally Administered vs. Inhaled Legal Market Cannabis: Cannabinoids Exposure, Intoxication, and Impairment. Psychopharmacology, 1-13.
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Karoly HC, Milburn, MA, Brooks-Russell, A, Brown, M, Streufert, J, Bryan, AD, Lovrich, NP, DeJong, W, & Bidwell, L. C. (2022). Effects of High Potency Cannabis on Psychomotor Performance in Frequent Cannabis Users.
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Gibson, L. P., Karoly, H. C., Ellingson, J. M., Klawitter, J., Sempio, C., Squeri, J. E., Bryan, A D., Bidwell, L. C., & Hutchison, K. E. (2022). Effects of cannabidiol in cannabis flower: Implications for harm reduction. PDF

Bidwell, L. C., Drennan, M. L., Karoly, H. C., Bryan, A. D., & Hutchison, K. (2021). Cannabis Exposure, Intoxication, and Mood Effects After Use of High Potency THC-Dominant vs. CBD-Dominant Cannabis Concentrates.

Drennan, M. L., Karoly, H. C., Bryan, A. D., Hutchison, K. E., & Bidwell, L. C. (2021). Acute objective and subjective intoxication effects of legal-market high potency THC-dominant versus CBD-dominant cannabis concentrates. Scientific reports, 11(1), 1-10
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Karoly, H. C., Skrzynski, C. J., Moe, E. N., Bryan, A. D., & Hutchison, K. E. (2021). Exploring relationships between alcohol consumption, inflammation and brain structure in a heavy drinking sample. Alcoholism: Clinical and Experimental Research, 45(11) 2256-2270.
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Karoly, H. C., Skrzynski, C.J., Moe, E., Bryan, A. D., & Hutchison, K. E. (2021). Investigating Associations Between Inflammatory Biomarkers, Gray Matter, Neurofilament Light, and Cognitive Performance in Healthy Older Adults. Frontiers in Aging Neuroscience, 547.
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Bidwell, L. C., Martin‐Willett, R., & Karoly, H. C. (2021). Advancing the science on cannabis concentrates and behavioural health. Drug and Alcohol Review.
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Karoly, H. C., Mueller, R. L., Andrade, C. C., Hutchison, K. E. (2021). THC and CBD effects on alcohol use among alcohol and cannabis co-users. PDF

Karoly HC, Ross MJ, Prince MA, Zabelski AE, & KE Hutchison. Effects of cannabis use on alcohol consumption in a sample of treatment-engaged heavy drinkers in Colorado. Addiction (2021).
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Karoly, H. C., Andrade, C. C., Zabelski, A. S., Bidwell, L. C., Hutchison, K. E. (2021). Exploring alcohol and cannabis co-use patterns among regular cannabis users and treatment-seeking heavy drinkers. PDF

Hutchison, K.E., Karoly, H. C., Ellingson, J. M., & Watson, K. (2021). Associations between gut microbiota and resting state functional connectivity in a sample of treatment seeking heavy drinkers. PDF

Karoly, H. C., Andrade, C. C., Mueller, R. L., & Hutchison, K. E. (2020). Investigating relationships between alcohol and cannabis use in an online survey of cannabis users: A focus on cannabinoid content and cannabis for medical purposes. Frontiers in Psychiatry, 11, 1509.
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Martin-Willett, R., Ellingson, J. E., Fries, J., Helmuth, T., Karoly, H., Giordano, G., … & Bryan, A. D. (2020). Few Structural Brain Changes Associated With Moderate-Intensity Interval Training and Low-Intensity Continuous Training in a Randomized Trial of Fitness and Older Adults. Journal of Aging and Physical Activity, 1(aop), 1-11.
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Bidwell, L.C., Ellingson, J., Karoly, H.C., YorkWilliams, S., Hitchcock, L.H., Tracy, B., Klawitter, J., Sempio, C., Bryan. A., Hutchison, K.E. (2020). Naturalistic Administration of Cannabis Flower and Concentrates: Cannabinoid Blood Levels, Subjective Intoxication, Cognition, and Motor Function. JAMA Psychiatry.
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Farokhnia, M., Berger, AL., Karoly, H.C., Hwa, L,S., & Varodayan, F. P. (2020). The promise of neuroimmune targets for treating drug addiction and other psychiatric disorders: G-CSF exemplification. Frontiers in Psychiatry, Addictive Disorders
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Karoly, H.C., Mueller, R.L., Bidwell, L.C., & Hutchison, K. E. (2020). Cannabinoids and the Microbiota-Gut-Brain-Axis: Emerging Effects of Cannabidiol and Potential Applications to Alcohol Use Disorders. Alcoholism: Clinical and Experimental Research, 44(2), 340-353.
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Gruber, J., Villanueva, C., Burr, E., Purcell, J.R., Weston, L & Karoly, H.C. (2020). Understanding and Taking Stock of Positive Emotions. Social and Personality Psychology Compass.
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Thayer, R.E., Hansen, N.S., Prashad, S., Karoly, H.C., Filbey, F., Bryan, A.D., & Feldstein Ewing, S.W. (2020). Recent tobacco use has widespread associations with adolescent white matter microstructure. Addictive Behaviors, 101, 106-152.
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Karoly, H.C., Ross, J.M., Ellingson, J.M., and Feldstein Ewing, S.W. (2020). Exploring Cannabis and Alcohol Co-Use in Adolescents: A Narrative Review of the Evidence. Journal of Dual Diagnosis, 1-17.
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Liu, Y., van den Wildenberg, W. P., de Graaf, Y., Ames, S. L., Baldacchino, A., Ragnhild, B,…Karoly, H.C…. & Colzato, L. S. (2019). Is poly-substance use associated with impaired inhibitory control? A mega-analysis controlling for confounders. Neuroscience & Biobehavioral Reviews.
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Karoly, H. C., Schacht, J. P., Jacobus, J., Meredith, L. R., Taylor, C. T., Tapert, S. F., Gray, K. M., & Squeglia, L. M. (2019). Preliminary evidence that computerized approach avoidance training is not associated with changes in fMRI cannabis cue reactivity in non-treatment-seeking adolescent cannabis users. Drug and Alcohol Dependence, 200, 145-152.
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Karoly, H. C., Schacht, J. P., Meredith, L. R., Jacobus, J., Tapert, S. F., Gray, K. M., & Squeglia, L. M. (2019). Investigating a novel fMRI cannabis cue reactivity task in youth. Addictive behaviors, 89, 20-28.
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Karoly, H.C., Ellingson J.M., & Hutchison K.E. (2018) TLR4 methylation moderates subjective responses to an intravenous ethanol infusion in human subjects. Alcohol and Alcoholism 53(6), 650-658.
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Gardiner, C. K., Karoly, H. C., Thayer, R. E., Gillman, A. S., Sabbineni, A., & Bryan, A. D. (2018). Neural activation during delay discounting is associated with 6-month change in risky sexual behavior in adolescents. Annals of Behavioral Medicine, 52(5) 356-366.
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Bidwell, L.C., Karoly, H.C., Thayer, R.E., Claus, E.D., Bryan A.B., Weiland, B.J., YorkWilliams, S., & Hutchison, K.E. (2019). DRD2 Promoter Methylation and Measures of Alcohol Reward: Functional Activation of Reward Circuits and Clinical Severity. Addiction Biology, 24 (3), 539-548.
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Marceau K., Bidwell L.C., Karoly H.C., Schettini Evans A., Todorov A.A., Palmer R.H., Heath A., & Knopik, V.S. (2018) Within-family effects of smoking during pregnancy on ADHD: the importance of phenotype. Journal of Abnormal Child Psychology, 46(4) 685-699.
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Karoly, H. C., Bidwell, L., Mueller, R., & Hutchison, K. (2017). Investigating the relationships between alcohol consumption, cannabis use and circulating cytokines: A preliminary analysis. Alcoholism: Clinical and Experimental Research, 42(3) 531-539.
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Thayer, R. E., YorkWilliams, S., Karoly, H. C., Sabbineni, A., Ewing, S. F., Bryan, A. D., and Hutchison, K. E. (2017) Structural neuroimaging correlates of alcohol and cannabis use in adolescents and adults. Addiction, 112: 2144–2154.
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Karoly H.C., Thayer R.E., Hagerty S.L., & Hutchison K.E. (2017) TLR4 methylation moderates the relationship between alcohol use severity and gray matter loss. Journal of Studies on Alcohol and Drugs, 78(5), 696–705.

Bidwell L.C., Karoly, H.C., Bryan A.D., & K.E. Hutchison (2017). ADHD symptoms impact smoking outcomes and withdrawal in response to varenicline treatment for smoking cessation. Drug and Alcohol Dependence, 179, 18-24
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Bidwell, L. C., Marceau, K., Brick, L. A., Karoly, H. C., Todorov, A. A., Palmer, R. H., … & Knopik, V. S. (2017). Prenatal exposure effects on early adolescent substance use: Preliminary evidence from a genetically informed Bayesian approach. Journal of Studies on Alcohol and Drugs, 78(5), 789-794.

Gardiner, C. K., Karoly, H. C., & Bryan, A. D. (2016). Commentary: Differential associations between obesity and behavioral measures of impulsivity. Frontiers in Psychology, 7, 949.
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Karoly H.C., YorkWilliams S.L., & Hutchison, K.E. (2015). Clinical neuroscience of addiction: Similarities and differences between alcohol and other drugs. Alcoholism Clinical and Experimental Research, 39(11), 2073-2084.
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Karoly H.C., Bryan A.D., Weiland B.J., Mayer A., Dodd A. & Feldstein Ewing S.W. (2015). Does incentive-elicited nucleus accumbens activation differ by substance of abuse? An examination with adolescents. Developmental Cognitive Neuroscience, 16, 5-15.
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Karoly H.C., Callahan T., Schmiege S.J., & Feldstein Ewing S.W. (2015). Evaluating the Hispanic Paradox in the context of adolescent risky sexual behavior: The role of parent monitoring. Journal of Pediatric Psychology, 41, 429-440.
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Littlewood, R.A., Claus, E.D., Arenella P., Bogenschutz, M., Karoly H.C., Feldstein Ewing, S.F., & Hutchison K.E (2014). Dose specific effects of olanzapine in the treatment of alcohol dependence. Psychopharmacology,232(7), 1-8.
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Karoly H.C., Hagerty, S.L., & Hutchison, K.E. (2014). Developing neurobiological endophenotypes that reflect failure to control alcohol consumption and dependence. Current Addiction Reports, 1(1), 10-18.
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Karoly, H.C., Weiland, B.J., Sabbineni, A., & Hutchison, K.E. (2014). Preliminary functional MRI results from a combined stop-signal alcohol-cue task. Journal of Studies on Alcohol and Drugs, 75(4), 664-673.

Feldstein Ewing, S.W., Karoly, H.C., & Hutchison, K.E. (2014). Commentary on Culverhouse et al. (2014): How genomics can bring us towards health equity. Addiction, 109(5), 823-824.
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Harlaar, N., Bryan, A.D., Thayer, R.E., Karoly, H.C., Oien, N., & Hutchison, K.E. (2013). Methylation of a CpG site near the ALDH1A2 gene is associated with loss of control over drinking and related phenotypes. Alcoholism: Clinical and Experimental Research, 38(3), 713-721.
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Karoly, H.C., Harlaar, N., & Hutchison, K.E. (2013). Substance use disorders: a theory-driven approach to the integration of genetics and neuroimaging. Annals of the New York Academy of Sciences, 1282(1), 71-91.
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Karoly, H.C., Stevens, C.J., Thayer, R.E., Magnan, R.E., Bryan, A.D., & Hutchison, K.E. (2013). Aerobic exercise moderates the effect of heavy alcohol consumption on white matter damage. Alcoholism: Clinical and Experimental Research, 37(9), 1508-1515.
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Karoly, H.C., Stevens C.J., Magnan R.E., Harlaar, N., Bryan A.D., & Hutchison K.E. (2012), Genetic influences on physiological and subjective responses to an aerobic exercise session among sedentary adults. Journal of Cancer Epidemiology, 2012: 1-12.
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Karoly, H.C., & Hutchison K.E. (2012): Does stress contribute to the incubation of craving? Biological Psychiatry, 71(8), 39.
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BOOK CHAPTERS

Karoly, H.C., Hagerty, S.L., Weiland, B.J., & Hutchison, K.E. (2015). Advancing addiction research through the integration of genetics and neuroimaging. In S.J. Wilson (Ed.), The Wiley Handbook on the Cognitive Neuroscience of Addiction (pp. 407-439).
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Feldstein Ewing, S.W., Karoly, H.C., & Houck, J.M. (2015). Deconstructing the neural substrates of motivational interviewing. In Neuroimaging and Psychosocial Addiction Treatment. In S.W. Feldstein Ewing, K. Witkiewitz, and F. M. Filbey (Ed.), Neuroimaging and Psychosocial Addiction Treatment (pp. 231-243).

Stevens, C.J., Karoly, H.C., Magnan, R.E., & Bryan, A.D., (2013). From genes to behavior change: treatment response as an intermediate phenotype. In J. MacKillop & M.R. Munafò (Eds.), Genetic Influences on Addiction: An Intermediate Phenotype Approach, (pp. 327-344).
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